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Overview

Carisoprodol, (Generic Soma®) is a muscle relaxant, and is used with rest, physical therapy, and other measures to relax muscles and relieve pain and discomfort caused by strains, sprains, and other muscle injuries.

 

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Usage

Carisoprodol is sometimes prescribed for other uses; ask your doctor for more information.

Dosage

Carisoprodol comes as a 350mg or 500mg tablet to take by mouth. It usually is taken three times daily and at bedtime. It may be taken with or without food.

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Carisoprodol is a centrally-acting skeletal muscle relaxant.

It is a colorless, crystalline powder, having a mild characteristic odor and a bitter taste.

Carisoprodol is slightly soluble in water and freely soluble in alcohol, chloroform and acetone.

The drug’s solubility is practically independent of pH.

Carisoprodol is manufactured and marketed in the United States by Meda Pharmaceuticals Inc. under the brand name SOMA, and in the United Kingdom and other countries under the brand names Sanoma and Carisoma.

The drug is available by itself or mixed with aspirin and in one preparation (Soma Compound With Codeine) along with codeine and caffeine as well.

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On June 1, 1959 several American pharmacologists convened at Wayne State University in Detroit, Michigan to discuss a new drug.

The drug, originally thought to have antiseptic properties, was found to have central muscle relaxing properties.

It had been developed by Dr. Frank M. Berger at Wallace Laboratories and was named Carisoprodol.

Carisoprodol was developed on the basis of meprobamate, in the hope that it would have better muscle relaxing properties, less potential for abuse, and less risk of overdose than meprobamate.

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The substitution of one hydrogen atom with an isopropyl group on one of the carbamyl nitrogens was intended to yield a molecule with new pharmacological properties.

The brand name Soma is shared with the Soma/Haoma of ancient India, a drug mentioned in ancient Sanskrit writings.

Various classical and modern researchers have theorised that Soma/Haoma could be anything from ephedra or opium to mushrooms of the genus Amanita with hallucinogenic effects due to the anti-muscarinic drugs contained therein, or other anti-cholinergic-drug containing plant—or a still unknown hallucinogen, stimulant and/or narcotic of unknown chemical class and origin or even coca or other drugs ported from the Western Hemisphere by an as yet unknown pre-Viking, pre-Columbian contact.

Soma is also the name of the fictional drug featured in Aldous Huxley’s Brave New World.

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Carisoprodol is a carbamic acid ester.

Carisoprodols Systematic Name:

2-{[(aminocarbonyl)oxy]methyl}-2-methylpentyl isopropylcarbamate

Carisoprodol is a racemic mixture of two stereoisomers.

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350 mg of Carisoprodol (the recommened dose) is unlikely to cause adverse side effects other than somnolence.

(Somnolence or “drowsiness” is a state of near-sleep, a strong desire for sleep, or sleeping for unusually long periods)

Carisoprodol is well tolerated by the majority of patients for whom it is prescribed and produces no adverse effects in that same majority.

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These side effects can impair a persons ability to operate a vehicle or motorcycle, operate heavy machinery or machinery in general and impair ones ability to operate a firearm safely.

The side effects of Carisoprodol are especially prominent when taken with alcohol or medications containing alcohol (this should be avoided).

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Carisoprodol is a carbamic acid ester.

Carisoprodols Systematic Name:

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(Somnolence or “drowsiness” is a state of near-sleep, a strong desire for sleep, or sleeping for unusually long periods)

Carisoprodol is well tolerated by the majority of patients for whom it is prescribed and produces no adverse effects in that same majority.

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The side effects of Carisoprodol are especially prominent when taken with alcohol or medications containing alcohol (this should be avoided).

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While Carisoprodol is not a controlled substance in the US, as of February 2010 (under federal regulations), Carisoprodol is to be considered to be a schedule IV controlled substance by the states of Alabama, Arizona, Arkansas, Florida, Georgia, Hawaii, Indiana, Kentucky, Louisiana, Massachusetts, Minnesota, Mississippi, New Mexico, Nevada, Oklahoma, Oregon and Texas, Utah, and Washington State.

A few of these States will require a state “DPS” number as well as a DEA number for any and all controlled substances prescriptions.

In West Virginia, Carisoprodol is a Schedule III controlled substance .

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The remainder of the US States and Territories will fall under the standard DEA scheduling of this medication.
The DEA considers Carisoprodol a non-scheduled chemical which means that Carisoprodol is considered a general prescription medication by United States.

On March 26, 2010 the DEA issued a Notice of Hearing on proposed rule making in respect to the placement of Carisoprodol in schedule IV of the Controlled Substances Act.

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Carisoprodol is a muscle relaxant and is used with rest, physical therapy, and other measures to relax muscles and relieve pain and discomfort caused by strains, sprains, and other muscle injuries.

This medication is sometimes prescribed for other uses; ask your doctor for more information.

Carisoprodol comes as a 350 mg tablet to take by mouth.

It usually is taken three times daily and at bedtime.

It may be taken with or without food.

Carisoprodol is also known as: Soma®, Sanoma®, Carisoma®

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Carisoprodol is used primarily to treat muscle pain.

It contains a muscle relaxant (Carisoprodol) and aspirin.

Other Names

  • Soma Compound
  • Carisoprodol with Aspirin

How Safe Is Carisoprodol (Soma)?

Average Risk Rating
0:
Pregnancy Category
D
Black Box Warning:
No

Facts & Figures

Date Approved
12 Sep 1960
Est US Patients*
23,360
Generic Available
Yes
OTC Available
No

User Age Distribution*

0< 21  1021-39  6840-59  2260+

* Estimated number of US people currently taking Carisoprodol with Aspirin or its active ingredient based on population adjusted patient numbers registered with iGuard.

Other Resources